Metossipropandiolo
Brand names,
Metossipropandiolo
Analogs
Metossipropandiolo
Brand Names Mixture
Metossipropandiolo
Chemical_Formula
C10H14O4
Metossipropandiolo
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Metossipropandiolo
fda sheet
Metossipropandiolo
msds (material safety sheet)
Metossipropandiolo
Synthesis Reference
No information avaliable
Metossipropandiolo
Molecular Weight
198.216 g/mol
Metossipropandiolo
Melting Point
78.5 oC
Metossipropandiolo
H2O Solubility
50 mg/mL
Metossipropandiolo
State
Solid
Metossipropandiolo
LogP
0.95
Metossipropandiolo
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Metossipropandiolo
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Metossipropandiolo
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Metossipropandiolo
Absorption
Rapidly absorbed from the GI tract
Metossipropandiolo
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Metossipropandiolo
Patient Information
No information avaliable
Metossipropandiolo
Organisms Affected
Humans and other mammals