Guaiphenesin
Brand names,
Guaiphenesin
Analogs
Guaiphenesin
Brand Names Mixture
Guaiphenesin
Chemical_Formula
C10H14O4
Guaiphenesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphenesin
fda sheet
Guaiphenesin
msds (material safety sheet)
Guaiphenesin
Synthesis Reference
No information avaliable
Guaiphenesin
Molecular Weight
198.216 g/mol
Guaiphenesin
Melting Point
78.5 oC
Guaiphenesin
H2O Solubility
50 mg/mL
Guaiphenesin
State
Solid
Guaiphenesin
LogP
0.95
Guaiphenesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphenesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphenesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphenesin
Absorption
Rapidly absorbed from the GI tract
Guaiphenesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphenesin
Patient Information
No information avaliable
Guaiphenesin
Organisms Affected
Humans and other mammals