Glyceryl guaiacolate
Brand names,
Glyceryl guaiacolate
Analogs
Glyceryl guaiacolate
Brand Names Mixture
Glyceryl guaiacolate
Chemical_Formula
C10H14O4
Glyceryl guaiacolate
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl guaiacolate
fda sheet
Glyceryl guaiacolate
msds (material safety sheet)
Glyceryl guaiacolate
Synthesis Reference
No information avaliable
Glyceryl guaiacolate
Molecular Weight
198.216 g/mol
Glyceryl guaiacolate
Melting Point
78.5 oC
Glyceryl guaiacolate
H2O Solubility
50 mg/mL
Glyceryl guaiacolate
State
Solid
Glyceryl guaiacolate
LogP
0.95
Glyceryl guaiacolate
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl guaiacolate
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl guaiacolate
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl guaiacolate
Absorption
Rapidly absorbed from the GI tract
Glyceryl guaiacolate
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl guaiacolate
Patient Information
No information avaliable
Glyceryl guaiacolate
Organisms Affected
Humans and other mammals