Guaicol glycerine ether
Brand names,
Guaicol glycerine ether
Analogs
Guaicol glycerine ether
Brand Names Mixture
Guaicol glycerine ether
Chemical_Formula
C10H14O4
Guaicol glycerine ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaicol glycerine ether
fda sheet
Guaicol glycerine ether
msds (material safety sheet)
Guaicol glycerine ether
Synthesis Reference
No information avaliable
Guaicol glycerine ether
Molecular Weight
198.216 g/mol
Guaicol glycerine ether
Melting Point
78.5 oC
Guaicol glycerine ether
H2O Solubility
50 mg/mL
Guaicol glycerine ether
State
Solid
Guaicol glycerine ether
LogP
0.95
Guaicol glycerine ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaicol glycerine ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaicol glycerine ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaicol glycerine ether
Absorption
Rapidly absorbed from the GI tract
Guaicol glycerine ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaicol glycerine ether
Patient Information
No information avaliable
Guaicol glycerine ether
Organisms Affected
Humans and other mammals