Glyceryl guaiacyl ether
Brand names,
Glyceryl guaiacyl ether
Analogs
Glyceryl guaiacyl ether
Brand Names Mixture
Glyceryl guaiacyl ether
Chemical_Formula
C10H14O4
Glyceryl guaiacyl ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl guaiacyl ether
fda sheet
Glyceryl guaiacyl ether
msds (material safety sheet)
Glyceryl guaiacyl ether
Synthesis Reference
No information avaliable
Glyceryl guaiacyl ether
Molecular Weight
198.216 g/mol
Glyceryl guaiacyl ether
Melting Point
78.5 oC
Glyceryl guaiacyl ether
H2O Solubility
50 mg/mL
Glyceryl guaiacyl ether
State
Solid
Glyceryl guaiacyl ether
LogP
0.95
Glyceryl guaiacyl ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl guaiacyl ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl guaiacyl ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl guaiacyl ether
Absorption
Rapidly absorbed from the GI tract
Glyceryl guaiacyl ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl guaiacyl ether
Patient Information
No information avaliable
Glyceryl guaiacyl ether
Organisms Affected
Humans and other mammals