Reduton
Brand names,
Reduton
Analogs
Reduton
Brand Names Mixture
Reduton
Chemical_Formula
C10H14O4
Reduton
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Reduton
fda sheet
Reduton
msds (material safety sheet)
Reduton
Synthesis Reference
No information avaliable
Reduton
Molecular Weight
198.216 g/mol
Reduton
Melting Point
78.5 oC
Reduton
H2O Solubility
50 mg/mL
Reduton
State
Solid
Reduton
LogP
0.95
Reduton
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Reduton
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Reduton
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Reduton
Absorption
Rapidly absorbed from the GI tract
Reduton
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Reduton
Patient Information
No information avaliable
Reduton
Organisms Affected
Humans and other mammals