Guayanesin
Brand names,
Guayanesin
Analogs
Guayanesin
Brand Names Mixture
Guayanesin
Chemical_Formula
C10H14O4
Guayanesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guayanesin
fda sheet
Guayanesin
msds (material safety sheet)
Guayanesin
Synthesis Reference
No information avaliable
Guayanesin
Molecular Weight
198.216 g/mol
Guayanesin
Melting Point
78.5 oC
Guayanesin
H2O Solubility
50 mg/mL
Guayanesin
State
Solid
Guayanesin
LogP
0.95
Guayanesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guayanesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guayanesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guayanesin
Absorption
Rapidly absorbed from the GI tract
Guayanesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guayanesin
Patient Information
No information avaliable
Guayanesin
Organisms Affected
Humans and other mammals