Gaiamar
Brand names,
Gaiamar
Analogs
Gaiamar
Brand Names Mixture
Gaiamar
Chemical_Formula
C10H14O4
Gaiamar
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Gaiamar
fda sheet
Gaiamar
msds (material safety sheet)
Gaiamar
Synthesis Reference
No information avaliable
Gaiamar
Molecular Weight
198.216 g/mol
Gaiamar
Melting Point
78.5 oC
Gaiamar
H2O Solubility
50 mg/mL
Gaiamar
State
Solid
Gaiamar
LogP
0.95
Gaiamar
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Gaiamar
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Gaiamar
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Gaiamar
Absorption
Rapidly absorbed from the GI tract
Gaiamar
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Gaiamar
Patient Information
No information avaliable
Gaiamar
Organisms Affected
Humans and other mammals