Pneumomist
Brand names,
Pneumomist
Analogs
Pneumomist
Brand Names Mixture
Pneumomist
Chemical_Formula
C10H14O4
Pneumomist
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Pneumomist
fda sheet
Pneumomist
msds (material safety sheet)
Pneumomist
Synthesis Reference
No information avaliable
Pneumomist
Molecular Weight
198.216 g/mol
Pneumomist
Melting Point
78.5 oC
Pneumomist
H2O Solubility
50 mg/mL
Pneumomist
State
Solid
Pneumomist
LogP
0.95
Pneumomist
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Pneumomist
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Pneumomist
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Pneumomist
Absorption
Rapidly absorbed from the GI tract
Pneumomist
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Pneumomist
Patient Information
No information avaliable
Pneumomist
Organisms Affected
Humans and other mammals