Guaiphenesine
Brand names,
Guaiphenesine
Analogs
Guaiphenesine
Brand Names Mixture
Guaiphenesine
Chemical_Formula
C10H14O4
Guaiphenesine
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphenesine
fda sheet
Guaiphenesine
msds (material safety sheet)
Guaiphenesine
Synthesis Reference
No information avaliable
Guaiphenesine
Molecular Weight
198.216 g/mol
Guaiphenesine
Melting Point
78.5 oC
Guaiphenesine
H2O Solubility
50 mg/mL
Guaiphenesine
State
Solid
Guaiphenesine
LogP
0.95
Guaiphenesine
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphenesine
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphenesine
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphenesine
Absorption
Rapidly absorbed from the GI tract
Guaiphenesine
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphenesine
Patient Information
No information avaliable
Guaiphenesine
Organisms Affected
Humans and other mammals