Guaiamar
Brand names,
Guaiamar
Analogs
Guaiamar
Brand Names Mixture
Guaiamar
Chemical_Formula
C10H14O4
Guaiamar
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiamar
fda sheet
Guaiamar
msds (material safety sheet)
Guaiamar
Synthesis Reference
No information avaliable
Guaiamar
Molecular Weight
198.216 g/mol
Guaiamar
Melting Point
78.5 oC
Guaiamar
H2O Solubility
50 mg/mL
Guaiamar
State
Solid
Guaiamar
LogP
0.95
Guaiamar
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiamar
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiamar
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiamar
Absorption
Rapidly absorbed from the GI tract
Guaiamar
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiamar
Patient Information
No information avaliable
Guaiamar
Organisms Affected
Humans and other mammals