Guaiacol glycerol ether
Brand names,
Guaiacol glycerol ether
Analogs
Guaiacol glycerol ether
Brand Names Mixture
Guaiacol glycerol ether
Chemical_Formula
C10H14O4
Guaiacol glycerol ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacol glycerol ether
fda sheet
Guaiacol glycerol ether
msds (material safety sheet)
Guaiacol glycerol ether
Synthesis Reference
No information avaliable
Guaiacol glycerol ether
Molecular Weight
198.216 g/mol
Guaiacol glycerol ether
Melting Point
78.5 oC
Guaiacol glycerol ether
H2O Solubility
50 mg/mL
Guaiacol glycerol ether
State
Solid
Guaiacol glycerol ether
LogP
0.95
Guaiacol glycerol ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacol glycerol ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacol glycerol ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacol glycerol ether
Absorption
Rapidly absorbed from the GI tract
Guaiacol glycerol ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacol glycerol ether
Patient Information
No information avaliable
Guaiacol glycerol ether
Organisms Affected
Humans and other mammals