Tolyn
Brand names,
Tolyn
Analogs
Tolyn
Brand Names Mixture
Tolyn
Chemical_Formula
C10H14O4
Tolyn
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Tolyn
fda sheet
Tolyn
msds (material safety sheet)
Tolyn
Synthesis Reference
No information avaliable
Tolyn
Molecular Weight
198.216 g/mol
Tolyn
Melting Point
78.5 oC
Tolyn
H2O Solubility
50 mg/mL
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State
Solid
Tolyn
LogP
0.95
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Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Tolyn
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Tolyn
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Tolyn
Absorption
Rapidly absorbed from the GI tract
Tolyn
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Tolyn
Patient Information
No information avaliable
Tolyn
Organisms Affected
Humans and other mammals