Bronchol
Brand names,
Bronchol
Analogs
Bronchol
Brand Names Mixture
Bronchol
Chemical_Formula
C10H14O4
Bronchol
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Bronchol
fda sheet
Bronchol
msds (material safety sheet)
Bronchol
Synthesis Reference
No information avaliable
Bronchol
Molecular Weight
198.216 g/mol
Bronchol
Melting Point
78.5 oC
Bronchol
H2O Solubility
50 mg/mL
Bronchol
State
Solid
Bronchol
LogP
0.95
Bronchol
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Bronchol
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Bronchol
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Bronchol
Absorption
Rapidly absorbed from the GI tract
Bronchol
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Bronchol
Patient Information
No information avaliable
Bronchol
Organisms Affected
Humans and other mammals