Oreson
Brand names,
Oreson
Analogs
Oreson
Brand Names Mixture
Oreson
Chemical_Formula
C10H14O4
Oreson
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Oreson
fda sheet
Oreson
msds (material safety sheet)
Oreson
Synthesis Reference
No information avaliable
Oreson
Molecular Weight
198.216 g/mol
Oreson
Melting Point
78.5 oC
Oreson
H2O Solubility
50 mg/mL
Oreson
State
Solid
Oreson
LogP
0.95
Oreson
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Oreson
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Oreson
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Oreson
Absorption
Rapidly absorbed from the GI tract
Oreson
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Oreson
Patient Information
No information avaliable
Oreson
Organisms Affected
Humans and other mammals