Guaiacolglicerinetere
Brand names,
Guaiacolglicerinetere
Analogs
Guaiacolglicerinetere
Brand Names Mixture
Guaiacolglicerinetere
Chemical_Formula
C10H14O4
Guaiacolglicerinetere
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacolglicerinetere
fda sheet
Guaiacolglicerinetere
msds (material safety sheet)
Guaiacolglicerinetere
Synthesis Reference
No information avaliable
Guaiacolglicerinetere
Molecular Weight
198.216 g/mol
Guaiacolglicerinetere
Melting Point
78.5 oC
Guaiacolglicerinetere
H2O Solubility
50 mg/mL
Guaiacolglicerinetere
State
Solid
Guaiacolglicerinetere
LogP
0.95
Guaiacolglicerinetere
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacolglicerinetere
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacolglicerinetere
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacolglicerinetere
Absorption
Rapidly absorbed from the GI tract
Guaiacolglicerinetere
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacolglicerinetere
Patient Information
No information avaliable
Guaiacolglicerinetere
Organisms Affected
Humans and other mammals