Guajacuran
Brand names,
Guajacuran
Analogs
Guajacuran
Brand Names Mixture
Guajacuran
Chemical_Formula
C10H14O4
Guajacuran
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guajacuran
fda sheet
Guajacuran
msds (material safety sheet)
Guajacuran
Synthesis Reference
No information avaliable
Guajacuran
Molecular Weight
198.216 g/mol
Guajacuran
Melting Point
78.5 oC
Guajacuran
H2O Solubility
50 mg/mL
Guajacuran
State
Solid
Guajacuran
LogP
0.95
Guajacuran
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guajacuran
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guajacuran
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guajacuran
Absorption
Rapidly absorbed from the GI tract
Guajacuran
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guajacuran
Patient Information
No information avaliable
Guajacuran
Organisms Affected
Humans and other mammals