Respenyl
Brand names,
Respenyl
Analogs
Respenyl
Brand Names Mixture
Respenyl
Chemical_Formula
C10H14O4
Respenyl
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Respenyl
fda sheet
Respenyl
msds (material safety sheet)
Respenyl
Synthesis Reference
No information avaliable
Respenyl
Molecular Weight
198.216 g/mol
Respenyl
Melting Point
78.5 oC
Respenyl
H2O Solubility
50 mg/mL
Respenyl
State
Solid
Respenyl
LogP
0.95
Respenyl
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Respenyl
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Respenyl
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Respenyl
Absorption
Rapidly absorbed from the GI tract
Respenyl
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Respenyl
Patient Information
No information avaliable
Respenyl
Organisms Affected
Humans and other mammals