Amonidrin
Brand names,
Amonidrin
Analogs
Amonidrin
Brand Names Mixture
Amonidrin
Chemical_Formula
C10H14O4
Amonidrin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Amonidrin
fda sheet
Amonidrin
msds (material safety sheet)
Amonidrin
Synthesis Reference
No information avaliable
Amonidrin
Molecular Weight
198.216 g/mol
Amonidrin
Melting Point
78.5 oC
Amonidrin
H2O Solubility
50 mg/mL
Amonidrin
State
Solid
Amonidrin
LogP
0.95
Amonidrin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Amonidrin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Amonidrin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Amonidrin
Absorption
Rapidly absorbed from the GI tract
Amonidrin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Amonidrin
Patient Information
No information avaliable
Amonidrin
Organisms Affected
Humans and other mammals