Nitrofurol
Brand names,
Nitrofurol
Analogs
Nitrofurol
Brand Names Mixture
Nitrofurol
Chemical_Formula
C6H6N4O4
Nitrofurol
RX_link
No information avaliable
Nitrofurol
fda sheet
Nitrofurol
msds (material safety sheet)
Nitrofurol
Synthesis Reference
No information avaliable
Nitrofurol
Molecular Weight
198.136 g/mol
Nitrofurol
Melting Point
238 oC
Nitrofurol
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofurol
State
Solid
Nitrofurol
LogP
0.517
Nitrofurol
Dosage Forms
Ointment
Nitrofurol
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofurol
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofurol
Absorption
Well absorbed.
Nitrofurol
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofurol
Patient Information
No information avaliable
Nitrofurol
Organisms Affected
Gram negative and gram positive bacteria