Sanfuran
Brand names,
Sanfuran
Analogs
Sanfuran
Brand Names Mixture
Sanfuran
Chemical_Formula
C6H6N4O4
Sanfuran
RX_link
No information avaliable
Sanfuran
fda sheet
Sanfuran
msds (material safety sheet)
Sanfuran
Synthesis Reference
No information avaliable
Sanfuran
Molecular Weight
198.136 g/mol
Sanfuran
Melting Point
238 oC
Sanfuran
H2O Solubility
210 mg/L (Approximately 50%)
Sanfuran
State
Solid
Sanfuran
LogP
0.517
Sanfuran
Dosage Forms
Ointment
Sanfuran
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Sanfuran
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Sanfuran
Absorption
Well absorbed.
Sanfuran
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Sanfuran
Patient Information
No information avaliable
Sanfuran
Organisms Affected
Gram negative and gram positive bacteria