Furaziline
Brand names,
Furaziline
Analogs
Furaziline
Brand Names Mixture
Furaziline
Chemical_Formula
C6H6N4O4
Furaziline
RX_link
No information avaliable
Furaziline
fda sheet
Furaziline
msds (material safety sheet)
Furaziline
Synthesis Reference
No information avaliable
Furaziline
Molecular Weight
198.136 g/mol
Furaziline
Melting Point
238 oC
Furaziline
H2O Solubility
210 mg/L (Approximately 50%)
Furaziline
State
Solid
Furaziline
LogP
0.517
Furaziline
Dosage Forms
Ointment
Furaziline
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furaziline
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furaziline
Absorption
Well absorbed.
Furaziline
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furaziline
Patient Information
No information avaliable
Furaziline
Organisms Affected
Gram negative and gram positive bacteria