Nitrofuraldehyde Semicarbazone
Brand names,
Nitrofuraldehyde Semicarbazone
Analogs
Nitrofuraldehyde Semicarbazone
Brand Names Mixture
Nitrofuraldehyde Semicarbazone
Chemical_Formula
C6H6N4O4
Nitrofuraldehyde Semicarbazone
RX_link
No information avaliable
Nitrofuraldehyde Semicarbazone
fda sheet
Nitrofuraldehyde Semicarbazone
msds (material safety sheet)
Nitrofuraldehyde Semicarbazone
Synthesis Reference
No information avaliable
Nitrofuraldehyde Semicarbazone
Molecular Weight
198.136 g/mol
Nitrofuraldehyde Semicarbazone
Melting Point
238 oC
Nitrofuraldehyde Semicarbazone
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofuraldehyde Semicarbazone
State
Solid
Nitrofuraldehyde Semicarbazone
LogP
0.517
Nitrofuraldehyde Semicarbazone
Dosage Forms
Ointment
Nitrofuraldehyde Semicarbazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofuraldehyde Semicarbazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofuraldehyde Semicarbazone
Absorption
Well absorbed.
Nitrofuraldehyde Semicarbazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofuraldehyde Semicarbazone
Patient Information
No information avaliable
Nitrofuraldehyde Semicarbazone
Organisms Affected
Gram negative and gram positive bacteria