Nifucin
Brand names,
Nifucin
Analogs
Nifucin
Brand Names Mixture
Nifucin
Chemical_Formula
C6H6N4O4
Nifucin
RX_link
No information avaliable
Nifucin
fda sheet
Nifucin
msds (material safety sheet)
Nifucin
Synthesis Reference
No information avaliable
Nifucin
Molecular Weight
198.136 g/mol
Nifucin
Melting Point
238 oC
Nifucin
H2O Solubility
210 mg/L (Approximately 50%)
Nifucin
State
Solid
Nifucin
LogP
0.517
Nifucin
Dosage Forms
Ointment
Nifucin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nifucin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nifucin
Absorption
Well absorbed.
Nifucin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nifucin
Patient Information
No information avaliable
Nifucin
Organisms Affected
Gram negative and gram positive bacteria