Nitrozone
Brand names,
Nitrozone
Analogs
Nitrozone
Brand Names Mixture
Nitrozone
Chemical_Formula
C6H6N4O4
Nitrozone
RX_link
No information avaliable
Nitrozone
fda sheet
Nitrozone
msds (material safety sheet)
Nitrozone
Synthesis Reference
No information avaliable
Nitrozone
Molecular Weight
198.136 g/mol
Nitrozone
Melting Point
238 oC
Nitrozone
H2O Solubility
210 mg/L (Approximately 50%)
Nitrozone
State
Solid
Nitrozone
LogP
0.517
Nitrozone
Dosage Forms
Ointment
Nitrozone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrozone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrozone
Absorption
Well absorbed.
Nitrozone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrozone
Patient Information
No information avaliable
Nitrozone
Organisms Affected
Gram negative and gram positive bacteria