Furfurin
Brand names,
Furfurin
Analogs
Furfurin
Brand Names Mixture
Furfurin
Chemical_Formula
C6H6N4O4
Furfurin
RX_link
No information avaliable
Furfurin
fda sheet
Furfurin
msds (material safety sheet)
Furfurin
Synthesis Reference
No information avaliable
Furfurin
Molecular Weight
198.136 g/mol
Furfurin
Melting Point
238 oC
Furfurin
H2O Solubility
210 mg/L (Approximately 50%)
Furfurin
State
Solid
Furfurin
LogP
0.517
Furfurin
Dosage Forms
Ointment
Furfurin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furfurin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furfurin
Absorption
Well absorbed.
Furfurin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furfurin
Patient Information
No information avaliable
Furfurin
Organisms Affected
Gram negative and gram positive bacteria