Amifur
Brand names,
Amifur
Analogs
Amifur
Brand Names Mixture
Amifur
Chemical_Formula
C6H6N4O4
Amifur
RX_link
No information avaliable
Amifur
fda sheet
Amifur
msds (material safety sheet)
Amifur
Synthesis Reference
No information avaliable
Amifur
Molecular Weight
198.136 g/mol
Amifur
Melting Point
238 oC
Amifur
H2O Solubility
210 mg/L (Approximately 50%)
Amifur
State
Solid
Amifur
LogP
0.517
Amifur
Dosage Forms
Ointment
Amifur
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Amifur
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Amifur
Absorption
Well absorbed.
Amifur
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Amifur
Patient Information
No information avaliable
Amifur
Organisms Affected
Gram negative and gram positive bacteria