Spray-Dermis
Brand names,
Spray-Dermis
Analogs
Spray-Dermis
Brand Names Mixture
Spray-Dermis
Chemical_Formula
C6H6N4O4
Spray-Dermis
RX_link
No information avaliable
Spray-Dermis
fda sheet
Spray-Dermis
msds (material safety sheet)
Spray-Dermis
Synthesis Reference
No information avaliable
Spray-Dermis
Molecular Weight
198.136 g/mol
Spray-Dermis
Melting Point
238 oC
Spray-Dermis
H2O Solubility
210 mg/L (Approximately 50%)
Spray-Dermis
State
Solid
Spray-Dermis
LogP
0.517
Spray-Dermis
Dosage Forms
Ointment
Spray-Dermis
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Spray-Dermis
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Spray-Dermis
Absorption
Well absorbed.
Spray-Dermis
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Spray-Dermis
Patient Information
No information avaliable
Spray-Dermis
Organisms Affected
Gram negative and gram positive bacteria