Ibiofural
Brand names,
Ibiofural
Analogs
Ibiofural
Brand Names Mixture
Ibiofural
Chemical_Formula
C6H6N4O4
Ibiofural
RX_link
No information avaliable
Ibiofural
fda sheet
Ibiofural
msds (material safety sheet)
Ibiofural
Synthesis Reference
No information avaliable
Ibiofural
Molecular Weight
198.136 g/mol
Ibiofural
Melting Point
238 oC
Ibiofural
H2O Solubility
210 mg/L (Approximately 50%)
Ibiofural
State
Solid
Ibiofural
LogP
0.517
Ibiofural
Dosage Forms
Ointment
Ibiofural
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Ibiofural
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Ibiofural
Absorption
Well absorbed.
Ibiofural
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Ibiofural
Patient Information
No information avaliable
Ibiofural
Organisms Affected
Gram negative and gram positive bacteria