Monafuracin
Brand names,
Monafuracin
Analogs
Monafuracin
Brand Names Mixture
Monafuracin
Chemical_Formula
C6H6N4O4
Monafuracin
RX_link
No information avaliable
Monafuracin
fda sheet
Monafuracin
msds (material safety sheet)
Monafuracin
Synthesis Reference
No information avaliable
Monafuracin
Molecular Weight
198.136 g/mol
Monafuracin
Melting Point
238 oC
Monafuracin
H2O Solubility
210 mg/L (Approximately 50%)
Monafuracin
State
Solid
Monafuracin
LogP
0.517
Monafuracin
Dosage Forms
Ointment
Monafuracin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Monafuracin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Monafuracin
Absorption
Well absorbed.
Monafuracin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Monafuracin
Patient Information
No information avaliable
Monafuracin
Organisms Affected
Gram negative and gram positive bacteria