Becafurazone
Brand names,
Becafurazone
Analogs
Becafurazone
Brand Names Mixture
Becafurazone
Chemical_Formula
C6H6N4O4
Becafurazone
RX_link
No information avaliable
Becafurazone
fda sheet
Becafurazone
msds (material safety sheet)
Becafurazone
Synthesis Reference
No information avaliable
Becafurazone
Molecular Weight
198.136 g/mol
Becafurazone
Melting Point
238 oC
Becafurazone
H2O Solubility
210 mg/L (Approximately 50%)
Becafurazone
State
Solid
Becafurazone
LogP
0.517
Becafurazone
Dosage Forms
Ointment
Becafurazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Becafurazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Becafurazone
Absorption
Well absorbed.
Becafurazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Becafurazone
Patient Information
No information avaliable
Becafurazone
Organisms Affected
Gram negative and gram positive bacteria