Vadrocid
Brand names,
Vadrocid
Analogs
Vadrocid
Brand Names Mixture
Vadrocid
Chemical_Formula
C6H6N4O4
Vadrocid
RX_link
No information avaliable
Vadrocid
fda sheet
Vadrocid
msds (material safety sheet)
Vadrocid
Synthesis Reference
No information avaliable
Vadrocid
Molecular Weight
198.136 g/mol
Vadrocid
Melting Point
238 oC
Vadrocid
H2O Solubility
210 mg/L (Approximately 50%)
Vadrocid
State
Solid
Vadrocid
LogP
0.517
Vadrocid
Dosage Forms
Ointment
Vadrocid
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Vadrocid
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Vadrocid
Absorption
Well absorbed.
Vadrocid
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Vadrocid
Patient Information
No information avaliable
Vadrocid
Organisms Affected
Gram negative and gram positive bacteria