Nitrofurane
Brand names,
Nitrofurane
Analogs
Nitrofurane
Brand Names Mixture
Nitrofurane
Chemical_Formula
C6H6N4O4
Nitrofurane
RX_link
No information avaliable
Nitrofurane
fda sheet
Nitrofurane
msds (material safety sheet)
Nitrofurane
Synthesis Reference
No information avaliable
Nitrofurane
Molecular Weight
198.136 g/mol
Nitrofurane
Melting Point
238 oC
Nitrofurane
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofurane
State
Solid
Nitrofurane
LogP
0.517
Nitrofurane
Dosage Forms
Ointment
Nitrofurane
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofurane
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofurane
Absorption
Well absorbed.
Nitrofurane
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofurane
Patient Information
No information avaliable
Nitrofurane
Organisms Affected
Gram negative and gram positive bacteria