Coxistat
Brand names,
Coxistat
Analogs
Coxistat
Brand Names Mixture
Coxistat
Chemical_Formula
C6H6N4O4
Coxistat
RX_link
No information avaliable
Coxistat
fda sheet
Coxistat
msds (material safety sheet)
Coxistat
Synthesis Reference
No information avaliable
Coxistat
Molecular Weight
198.136 g/mol
Coxistat
Melting Point
238 oC
Coxistat
H2O Solubility
210 mg/L (Approximately 50%)
Coxistat
State
Solid
Coxistat
LogP
0.517
Coxistat
Dosage Forms
Ointment
Coxistat
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Coxistat
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Coxistat
Absorption
Well absorbed.
Coxistat
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Coxistat
Patient Information
No information avaliable
Coxistat
Organisms Affected
Gram negative and gram positive bacteria