Biofuracina
Brand names,
Biofuracina
Analogs
Biofuracina
Brand Names Mixture
Biofuracina
Chemical_Formula
C6H6N4O4
Biofuracina
RX_link
No information avaliable
Biofuracina
fda sheet
Biofuracina
msds (material safety sheet)
Biofuracina
Synthesis Reference
No information avaliable
Biofuracina
Molecular Weight
198.136 g/mol
Biofuracina
Melting Point
238 oC
Biofuracina
H2O Solubility
210 mg/L (Approximately 50%)
Biofuracina
State
Solid
Biofuracina
LogP
0.517
Biofuracina
Dosage Forms
Ointment
Biofuracina
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Biofuracina
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Biofuracina
Absorption
Well absorbed.
Biofuracina
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Biofuracina
Patient Information
No information avaliable
Biofuracina
Organisms Affected
Gram negative and gram positive bacteria