Furacine
Brand names,
Furacine
Analogs
Furacine
Brand Names Mixture
Furacine
Chemical_Formula
C6H6N4O4
Furacine
RX_link
No information avaliable
Furacine
fda sheet
Furacine
msds (material safety sheet)
Furacine
Synthesis Reference
No information avaliable
Furacine
Molecular Weight
198.136 g/mol
Furacine
Melting Point
238 oC
Furacine
H2O Solubility
210 mg/L (Approximately 50%)
Furacine
State
Solid
Furacine
LogP
0.517
Furacine
Dosage Forms
Ointment
Furacine
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furacine
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furacine
Absorption
Well absorbed.
Furacine
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furacine
Patient Information
No information avaliable
Furacine
Organisms Affected
Gram negative and gram positive bacteria