Biofurea
Brand names,
Biofurea
Analogs
Biofurea
Brand Names Mixture
Biofurea
Chemical_Formula
C6H6N4O4
Biofurea
RX_link
No information avaliable
Biofurea
fda sheet
Biofurea
msds (material safety sheet)
Biofurea
Synthesis Reference
No information avaliable
Biofurea
Molecular Weight
198.136 g/mol
Biofurea
Melting Point
238 oC
Biofurea
H2O Solubility
210 mg/L (Approximately 50%)
Biofurea
State
Solid
Biofurea
LogP
0.517
Biofurea
Dosage Forms
Ointment
Biofurea
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Biofurea
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Biofurea
Absorption
Well absorbed.
Biofurea
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Biofurea
Patient Information
No information avaliable
Biofurea
Organisms Affected
Gram negative and gram positive bacteria