Furaplast
Brand names,
Furaplast
Analogs
Furaplast
Brand Names Mixture
Furaplast
Chemical_Formula
C6H6N4O4
Furaplast
RX_link
No information avaliable
Furaplast
fda sheet
Furaplast
msds (material safety sheet)
Furaplast
Synthesis Reference
No information avaliable
Furaplast
Molecular Weight
198.136 g/mol
Furaplast
Melting Point
238 oC
Furaplast
H2O Solubility
210 mg/L (Approximately 50%)
Furaplast
State
Solid
Furaplast
LogP
0.517
Furaplast
Dosage Forms
Ointment
Furaplast
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furaplast
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furaplast
Absorption
Well absorbed.
Furaplast
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furaplast
Patient Information
No information avaliable
Furaplast
Organisms Affected
Gram negative and gram positive bacteria