Mastofuran
Brand names,
Mastofuran
Analogs
Mastofuran
Brand Names Mixture
Mastofuran
Chemical_Formula
C6H6N4O4
Mastofuran
RX_link
No information avaliable
Mastofuran
fda sheet
Mastofuran
msds (material safety sheet)
Mastofuran
Synthesis Reference
No information avaliable
Mastofuran
Molecular Weight
198.136 g/mol
Mastofuran
Melting Point
238 oC
Mastofuran
H2O Solubility
210 mg/L (Approximately 50%)
Mastofuran
State
Solid
Mastofuran
LogP
0.517
Mastofuran
Dosage Forms
Ointment
Mastofuran
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Mastofuran
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Mastofuran
Absorption
Well absorbed.
Mastofuran
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Mastofuran
Patient Information
No information avaliable
Mastofuran
Organisms Affected
Gram negative and gram positive bacteria