Nitrofural
Brand names,
Nitrofural
Analogs
Nitrofural
Brand Names Mixture
Nitrofural
Chemical_Formula
C6H6N4O4
Nitrofural
RX_link
No information avaliable
Nitrofural
fda sheet
Nitrofural
msds (material safety sheet)
Nitrofural
Synthesis Reference
No information avaliable
Nitrofural
Molecular Weight
198.136 g/mol
Nitrofural
Melting Point
238 oC
Nitrofural
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofural
State
Solid
Nitrofural
LogP
0.517
Nitrofural
Dosage Forms
Ointment
Nitrofural
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofural
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofural
Absorption
Well absorbed.
Nitrofural
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofural
Patient Information
No information avaliable
Nitrofural
Organisms Affected
Gram negative and gram positive bacteria