Nitrofuran
Brand names,
Nitrofuran
Analogs
Nitrofuran
Brand Names Mixture
Nitrofuran
Chemical_Formula
C6H6N4O4
Nitrofuran
RX_link
No information avaliable
Nitrofuran
fda sheet
Nitrofuran
msds (material safety sheet)
Nitrofuran
Synthesis Reference
No information avaliable
Nitrofuran
Molecular Weight
198.136 g/mol
Nitrofuran
Melting Point
238 oC
Nitrofuran
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofuran
State
Solid
Nitrofuran
LogP
0.517
Nitrofuran
Dosage Forms
Ointment
Nitrofuran
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofuran
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofuran
Absorption
Well absorbed.
Nitrofuran
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofuran
Patient Information
No information avaliable
Nitrofuran
Organisms Affected
Gram negative and gram positive bacteria