Furacilin
Brand names,
Furacilin
Analogs
Furacilin
Brand Names Mixture
Furacilin
Chemical_Formula
C6H6N4O4
Furacilin
RX_link
No information avaliable
Furacilin
fda sheet
Furacilin
msds (material safety sheet)
Furacilin
Synthesis Reference
No information avaliable
Furacilin
Molecular Weight
198.136 g/mol
Furacilin
Melting Point
238 oC
Furacilin
H2O Solubility
210 mg/L (Approximately 50%)
Furacilin
State
Solid
Furacilin
LogP
0.517
Furacilin
Dosage Forms
Ointment
Furacilin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furacilin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furacilin
Absorption
Well absorbed.
Furacilin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furacilin
Patient Information
No information avaliable
Furacilin
Organisms Affected
Gram negative and gram positive bacteria