Dynazone
Brand names,
Dynazone
Analogs
Dynazone
Brand Names Mixture
Dynazone
Chemical_Formula
C6H6N4O4
Dynazone
RX_link
No information avaliable
Dynazone
fda sheet
Dynazone
msds (material safety sheet)
Dynazone
Synthesis Reference
No information avaliable
Dynazone
Molecular Weight
198.136 g/mol
Dynazone
Melting Point
238 oC
Dynazone
H2O Solubility
210 mg/L (Approximately 50%)
Dynazone
State
Solid
Dynazone
LogP
0.517
Dynazone
Dosage Forms
Ointment
Dynazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Dynazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Dynazone
Absorption
Well absorbed.
Dynazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Dynazone
Patient Information
No information avaliable
Dynazone
Organisms Affected
Gram negative and gram positive bacteria