Furazina
Brand names,
Furazina
Analogs
Furazina
Brand Names Mixture
Furazina
Chemical_Formula
C6H6N4O4
Furazina
RX_link
No information avaliable
Furazina
fda sheet
Furazina
msds (material safety sheet)
Furazina
Synthesis Reference
No information avaliable
Furazina
Molecular Weight
198.136 g/mol
Furazina
Melting Point
238 oC
Furazina
H2O Solubility
210 mg/L (Approximately 50%)
Furazina
State
Solid
Furazina
LogP
0.517
Furazina
Dosage Forms
Ointment
Furazina
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furazina
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furazina
Absorption
Well absorbed.
Furazina
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furazina
Patient Information
No information avaliable
Furazina
Organisms Affected
Gram negative and gram positive bacteria