Furaldon
Brand names,
Furaldon
Analogs
Furaldon
Brand Names Mixture
Furaldon
Chemical_Formula
C6H6N4O4
Furaldon
RX_link
No information avaliable
Furaldon
fda sheet
Furaldon
msds (material safety sheet)
Furaldon
Synthesis Reference
No information avaliable
Furaldon
Molecular Weight
198.136 g/mol
Furaldon
Melting Point
238 oC
Furaldon
H2O Solubility
210 mg/L (Approximately 50%)
Furaldon
State
Solid
Furaldon
LogP
0.517
Furaldon
Dosage Forms
Ointment
Furaldon
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furaldon
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furaldon
Absorption
Well absorbed.
Furaldon
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furaldon
Patient Information
No information avaliable
Furaldon
Organisms Affected
Gram negative and gram positive bacteria