Furazone
Brand names,
Furazone
Analogs
Furazone
Brand Names Mixture
Furazone
Chemical_Formula
C6H6N4O4
Furazone
RX_link
No information avaliable
Furazone
fda sheet
Furazone
msds (material safety sheet)
Furazone
Synthesis Reference
No information avaliable
Furazone
Molecular Weight
198.136 g/mol
Furazone
Melting Point
238 oC
Furazone
H2O Solubility
210 mg/L (Approximately 50%)
Furazone
State
Solid
Furazone
LogP
0.517
Furazone
Dosage Forms
Ointment
Furazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furazone
Absorption
Well absorbed.
Furazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furazone
Patient Information
No information avaliable
Furazone
Organisms Affected
Gram negative and gram positive bacteria