Furaderm
Brand names,
Furaderm
Analogs
Furaderm
Brand Names Mixture
Furaderm
Chemical_Formula
C6H6N4O4
Furaderm
RX_link
No information avaliable
Furaderm
fda sheet
Furaderm
msds (material safety sheet)
Furaderm
Synthesis Reference
No information avaliable
Furaderm
Molecular Weight
198.136 g/mol
Furaderm
Melting Point
238 oC
Furaderm
H2O Solubility
210 mg/L (Approximately 50%)
Furaderm
State
Solid
Furaderm
LogP
0.517
Furaderm
Dosage Forms
Ointment
Furaderm
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furaderm
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furaderm
Absorption
Well absorbed.
Furaderm
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furaderm
Patient Information
No information avaliable
Furaderm
Organisms Affected
Gram negative and gram positive bacteria