Eldezol
Brand names,
Eldezol
Analogs
Eldezol
Brand Names Mixture
Eldezol
Chemical_Formula
C6H6N4O4
Eldezol
RX_link
No information avaliable
Eldezol
fda sheet
Eldezol
msds (material safety sheet)
Eldezol
Synthesis Reference
No information avaliable
Eldezol
Molecular Weight
198.136 g/mol
Eldezol
Melting Point
238 oC
Eldezol
H2O Solubility
210 mg/L (Approximately 50%)
Eldezol
State
Solid
Eldezol
LogP
0.517
Eldezol
Dosage Forms
Ointment
Eldezol
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Eldezol
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Eldezol
Absorption
Well absorbed.
Eldezol
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Eldezol
Patient Information
No information avaliable
Eldezol
Organisms Affected
Gram negative and gram positive bacteria