Monafuracis
Brand names,
Monafuracis
Analogs
Monafuracis
Brand Names Mixture
Monafuracis
Chemical_Formula
C6H6N4O4
Monafuracis
RX_link
No information avaliable
Monafuracis
fda sheet
Monafuracis
msds (material safety sheet)
Monafuracis
Synthesis Reference
No information avaliable
Monafuracis
Molecular Weight
198.136 g/mol
Monafuracis
Melting Point
238 oC
Monafuracis
H2O Solubility
210 mg/L (Approximately 50%)
Monafuracis
State
Solid
Monafuracis
LogP
0.517
Monafuracis
Dosage Forms
Ointment
Monafuracis
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Monafuracis
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Monafuracis
Absorption
Well absorbed.
Monafuracis
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Monafuracis
Patient Information
No information avaliable
Monafuracis
Organisms Affected
Gram negative and gram positive bacteria