Mammex
Brand names,
Mammex
Analogs
Mammex
Brand Names Mixture
Mammex
Chemical_Formula
C6H6N4O4
Mammex
RX_link
No information avaliable
Mammex
fda sheet
Mammex
msds (material safety sheet)
Mammex
Synthesis Reference
No information avaliable
Mammex
Molecular Weight
198.136 g/mol
Mammex
Melting Point
238 oC
Mammex
H2O Solubility
210 mg/L (Approximately 50%)
Mammex
State
Solid
Mammex
LogP
0.517
Mammex
Dosage Forms
Ointment
Mammex
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Mammex
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Mammex
Absorption
Well absorbed.
Mammex
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Mammex
Patient Information
No information avaliable
Mammex
Organisms Affected
Gram negative and gram positive bacteria